In a recent interview with FearNET Sam Raimi hints to the fact that a rumor about Morbius being the villain in Spider-Man 4 could actually be true. Sam has a coy, mischievous tone in his voice when he says:

Whaat? I don’t know anything about that.

I Guess They’re… umm, very appealing like the best of villains. They have some positive qualities, That is they can be very sexy and alluring, and umm they way in which they attack you is a very sensual it’s almost something you desire. You know the bat, we’re all scared of bats. Ew! so thats kind of cool. Some vampire stories go there some of them don’t obviously. But umm, that why I like the fact that there’s a cure against them in some of the lore like the garlic, or the cross. That’s really interesting, that there’s a way to stop them. There’s a whole story that can be made with all those elements so its got some real rules and laws. And then you could be turned into one of them, is interesting also. There’s a lot of enticing qualities for a story teller and audience.

He could also be hinting towards wanting to do a Vampire movie under his Ghost House Pictures label and just wanted to use this opportunity to screw with the fans. Only time will tell.